Biohacking is a broad term that can mean different things to people. It generally refers to human enhancement using cutting-edge tools and technologies, biology, and self-experimentation to enhance one’s physical or mental performance. The ultimate goal is not just a prolonged lifespan but an improved quality of life when we are on this earth.
LIFESTYLE HACKS
- Nutrition and Diet: Try and focus on a balanced and nutrient-rich diet. Consider adopting a Mediterranean or plant-based diet, focusing on lean white protein, associated with various health benefits and longevity. Avoid processed foods.
- Red Wine: Resveratrol is a natural polyphenol found in the skin of red grapes and is now available in a capsule. Resveratrol has been shown to activate specific longevity genes in animal studies, extending the lifespan of some organisms. This has led to a hypothesis that resveratrol might have similar effects on human longevity. Additionally, in certain regions of Italy, where red wine is consumed regularly but in moderation, human lifespans are much greater.
- Intermittent Fasting: This involves cycling between periods of eating and fasting. It may help regulate metabolism and cellular repair processes. Organisms starved of food for periods in labs show significant prolonging of their normal lifespan.
- Exercise: Regular physical activity has numerous health benefits, including improved cardiovascular health, weight management, and stress reduction. Several extensive studies support that something as simple as a brisk walk several times a week improves longevity.
- Sleep Optimization: Aim for quality sleep, as it is crucial to overall health and well-being. During deep sleep, the body undergoes essential cellular repair and regeneration processes. These mechanisms help repair damaged cells and tissues, slowing the aging process.
- Stress Management: Chronic stress can negatively impact health. Some studies suggest that chronic stress may accelerate cellular aging, possibly due to the effects of cortisol on telomeres (protective caps on the ends of chromosomes).
- Cold Exposure: The practice of cold exposure, such as cold showers, ice baths, or exposure to cold environments, has gained attention due to the concept of hormesis, which is the idea that exposure to cold stressors can trigger adaptive responses that promote health and longevity. Several animal studies have shown promising results regarding the effects of cold exposure on lifespan.
- Social Connections: Social connections can significantly affect lifespan and overall health.
CUTTING-EDGE BIOHACKS
These are for those willing to push the envelope and embrace the latest in cutting-edge scientific research. These are the biohacks of the future and the present. I have fully vetted them from a safety and efficacy standpoint, or I wouldn’t offer them. That said, most of the below are considered “off-label use.” This means the FDA has not explicitly approved its use in the manner it is being prescribed. A physician can prescribe off-label treatments after carefully reviewing the literature and with medical expertise.
- Metformin: Metformin is a widely used medication for managing type 2 diabetes, and some studies have suggested that it may benefit aging and age-related conditions. One of the main mechanisms proposed for Metformin's potential anti-aging effects is its ability to activate an enzyme called AMP-activated protein kinase (AMPK). Currently, human trials are looking at Metformin as an FDA-approved drug for longevity. The beauty is that Metformin is plant-based and is well-tolerated.
- CJCCCJC-1295/Ipamorelin, Sermorelin, or Tesamorelin: The above peptides may be used for various health and wellness purposes, including anti-aging. These peptides are called growth hormone secretagogues, which produce increased growth hormone release from a part of the brain known as the pituitary gland. This has potential benefits for many age-related conditions. Over time, most of my patients have experienced improved skin quality, increased muscle mass, reduced body fat, better sleep, and enhanced energy levels. Tesamorelin plays an even more specific role in mid-section fat and may even reduce fatty liver in patients.
- NAD+NAD+: NAD (Nicotinamide Adenine Dinucleotide) is a coenzyme found in all living cells, and it plays a crucial role in various biological processes, particularly in energy production and cellular metabolism. Due to its critical role in cellular functions, including DNA repair, NAD+ has garnered interest as a potential supplement to improve health and combat aging-related issues.
- MOTS-C: MOTS-C is a peptide released from the mitochondria (the energy-producer, or “powerhouse of the cell”). When given, MOTS-C increases aerobic endurance in animal and human studies.
- MOTS-C levels in 70–81-year-olds drop by nearly 21% compared to 18–30-year-old individuals.
- Increases skin collagen, which improves the aging effect of skin
- May improve glucose in type I and type II diabetes
- Decreases fat and inflammatory markers in post-menopausal women
- May slow the effects of Alzheimer’s Disease
- Reduces Methionine in the body, which in animal studies increased lifespan by 45%
Dasatinib and Quercetin: This combination, referred to as D&Q, has unbelievable potential in the anti-aging world. In 2015, scientists discovered that accumulated cells, known as “senescent cells,” play a key role in aging. Senescent cells form after a normal cell divides a finite number of times, then either dies (undergoes cellular apoptosis) or becomes dormant-or so we thought. It turns out that when cells become senescent, they enter a state called "cellular senescence." This process is a protective mechanism that prevents damaged or potentially harmful cells from replicating and becoming cancerous. However, while beneficial in the short term, accumulating these senescent cells over time (it is estimated that the average person at the time of death has 7% senescent cells in their body) can have detrimental effects on the body. Senescent cells secrete a range of molecules and inflammatory signals known as the senescence-associated secretory phenotype (SASP). The SASP’s can promote chronic inflammation, disrupt tissue structure, and negatively affect neighboring healthy cells, ultimately contributing to various age-related diseases and conditions. In a dramatic study, aged mice had their senescent cells removed, and in a short time, the mice had notable improvements in their fur and skin, reduced arthritis, and improved insulin resistance. Several ongoing human trials utilize substances called senolytics that destroy accumulated senescent cells.
Whereas Quercetin is an herb easily obtained in health food stores or online, Dasatinib is a medication that has only recently become available through compounding pharmacies, making it affordable to the general public.
If you are ready to invest in your health, if you want to turn back the clock and feel and look your very best, you should consider anti-aging therapy at the OB Men clinic. Call OBMen today to schedule your consultation with our anti-aging specialist, Dr. Darryl Camp.
Contact Us Today to Schedule Your Free In-person Or Virtual Consultation!
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Happy Victory Monday VII, narrowly 🤘
It's a Bye Week, so we're going to do some housekeeping, I love checking in Behind Enemy Lines each week to see what is going on at Oklahoma, Texas A&M, Georgia, Florida, etc - but with the last few weeks unfolding the way they have, what better time than now to utilize the famed quote of “Clean up your own backyard, before pointing your finger at your neighbors".
7 Things through 7 Wins
* Can we stop with the Tre Wisner focus on Offense, please?
Total Touches over the last 2 games...
- Tre Wisner: (42-181) = 4.3 yards per touch
- Jaydon Blue: (20-119-1) = 5.95 yards per touch
- Gunnar Helm: (10-108) = 10.8 yards per touch
- DeAndre Moore: (6-72-2) = 12 yards per touch
Total Touches over the first 6 games...
- Jerrick Gibson: (51-252-3) = 4.94 yards per touch
- Jaydon Blue: (75-374-6) = 4.99 yards per touch
- Tre Wisner: (54-348-2) = 6.44 yards per touch
- Isaiah Bond: (23-420-4) = 18.2 yards per touch
- Gunnar Helm: (21-311-2) = 14.8 yards per touch
THOUGHT: At this point, if you are upset with Jaydon Blue and don't want to feature him out of the backfield, let's see how Jerrick Gibson or Ryan Niblett look in SEC play with 10+ carries, it can't be that much worse than Tre Wisner from an efficiency standpoint.
** Quinn Ewers is coming off of his 2nd career two-game stretch of 36+ pass attempts, the first time was at the end of 2023 with a blitzing of the Oklahoma State Cowboys and a loss to Washington, the difference in those two sets of games.
In 2023, he threw for 770 yards and averaged 8.65 yards per attempt (13.1 per completion), and in the last two games he has 499 yards and is averaging 6.2 yards per attempt (9.6 per completion).
*** Quinn Ewers' aDOT (average depth of target) in 2024 is now 5.9 yards.. ranking 79th of 79 in the Power 5.
In Week 7-9, Quinn's aDOT was 5.8
In Week 1-3, Quinn's aDOT was 6.2
In 2023, Quinn's aDOT was 8.4
In 2022, Quinn's aDOT was 10.6
THOUGHT: Both of these data points lead me in a weird direction, believing there is a level of protection being built into these game plans from Sark, for Quinn. NFL Teams are not going to love watching film after film of Quinn throwing the football time after time behind the LOS and within 5 yards of the LOS, time after time. I understand getting your guys into space and utilizing speed, but Quinn has shown in prior years his ability to push the football, I don't know if it's because of the Offensive Line, getting hurt, getting hit or game plan, but it's not championship level football
**** Drop Rate among targeted receivers for Texas is 5.1% (7 drops), ranking 36th in America, in 2023 that number was 3.6% (10 drops), ranking 9th in America.
- Jaydon Blue 5 drops
- Tre Wisner 3 drops
- Isaiah Bond 2 drops
THOUGHT: More Running Back stuff... sigh
***** According to PFF, DJ Campbell is the 3rd worst Zone Run Blocking Offensive Lineman in the SEC.
THOUGHT: @Alex Dunlap I know it's PFF, but I'm about ready to call for Cole Hutson to start, DJ needs a week to rest or a wake up call..
****** Punter, Michael Kern has the Worst Net Punting (37.9 yards) and the Worst Hangtime (3.54 seconds), in the SEC.
THOUGHT: S/A @Ketchum for appointing this a worry in the pre-season, when nobody else cared to say anything, nor attack Punter in the portal
******* Trey Moore has 13 pressures over the last 3 weeks and has out-snapped Collins Simmons who has 3 pressures, 141 snaps to 79 in that time. During the previous 3 games, Moore had 100 snaps to Simmons' 91, while Simmons was out-pressuring Moore 6 to 1.
THOUGHT: The SEC is #JustDifferent, I love that Trey Moore is finally coming on strong in the run and pass rush game, not all that worried about Simmons, the depth in that room will allow Simmons to get his 2nd half of the year legs.
My Week 9 Orangebloods SEC Power Poll
1. Georgia (Idle)
2. Texas (-)
3. Texas A&M (+2)
4. Tennessee (-1)
5. Vanderbilt (+2)
6. Alabama (-)
7. LSU (-2)
8. Ole Miss (-)
9. South Carolina (Idle)
10. Florida (Idle)
11. Missouri (-)
12. Arkansas (+1)
13. Auburn (+1)
14. Kentucky (-2)
15. Oklahoma (-)
16. Mississippi State (-)
Super Explosives 2024 (20+ yard plays) - 57 total (3rd in CFB)
Texas continues to dominate downfield, they currently ranks 3rd in the country with 57 plays of 20+ yards, just behind the Miami Hurricanes (65) and Ole Miss (58).
-- 8 vs. Vanderbilt --
DeAndre Moore 31-yard reception from Quinn Ewers vs. Vandy
Amari Niblack 20-yard reception from Quinn Ewers vs. Vandy
DeAndre Moore 27-yard reception from Quinn Ewers vs. Vandy
Gunnar Helm 24-yard reception from Quinn Ewers vs. Vandy
DeAndre Moore 25-yard reception from Quinn Ewers vs. Vandy
Tre Wisner 20-yard rush vs. Vandy
Silas Bolden 24-yard reception from Quinn Ewers vs. Vandy
Jaydon Blue 23-yard rush vs. Vandy
-- 4 vs. Georgia --
Arch Manning 21-yard rush vs. Georgia
Matthew Golden 24-yard reception from Quinn Ewers vs. Georgia
Matthew Golden 34-yard reception from Quinn Ewers vs. Georgia
Gunnar Helm 23-yard reception from Quinn Ewers vs. Georgia
-- 9 vs. Oklahoma --
Gunnar Helm 21-yard reception from Quinn Ewers vs. Oklahoma
Gunnar Helm 30-yard reception from Matthew Golden vs. Oklahoma
Gunnar Helm 26-yard reception from Quinn Ewers vs. Oklahoma
Ryan Wingo 44-yard reception from Quinn Ewers vs. Oklahoma
Ryan Wingo 25-yard rush vs. Oklahoma
Tre Wisner 36-yard rush vs. Oklahoma
Tre Wisner 43-yard rush vs. Oklahoma
DeAndre Moore 26-yard reception from Quinn Ewers vs. Oklahoma
Matthew Golden 23-yard reception from Quinn Ewers vs. Oklahoma
-- 9 vs. Mississippi State --
Matthew Golden 22-yard reception from Arch Manning vs. Miss State
Isaiah Bond 27-yard reception from Arch Manning vs. Miss State
Isaiah Bond 26-yard rush vs. Miss State
DeAndre Moore 49-yard reception from Arch Manning vs. Miss State
DeAndre Moore 27-yard reception from Arch Manning vs. Miss State
Johntay Cook 31-yard reception from Arch Manning vs. Miss State
Arch Manning 26-yard rush vs. Miss State
Tre Wisner 38-yard rush vs. Miss State
Jaydon Blue 21-yard rush vs. Miss State
-- 5 vs. UL-Monroe --
Ryan Wingo 25-yard reception from Arch Manning vs. ULM
Matthew Golden 46-yard reception from Arch Manning vs. ULM
Isaiah Bond 56-yard reception from Arch Manning vs. ULM
Jaydon Blue 20-yard rush vs. ULM
Colin Page 20-yard rush vs. ULM
-- 7 vs. UTSA --
Gunnar Helm 49-yard reception from Quinn Ewers vs. Colorado State
Matthew Golden 20-yard reception from Arch Manning vs. UTSA
Ryan Wingo 36-yard reception from Arch Manning vs. UTSA
Ryan Wingo 75-yard reception from Arch Manning vs. UTSA
Isaiah Bond 51-yard reception from Arch Manning vs. UTSA
Arch Manning 67-yard rush vs. UTSA
Colin Page 23-yard rush vs. UTSA
-- 8 vs. Michigan --
Gunnar Helm 21-yard reception from Quinn Ewers vs. Michigan
Gunnar Helm 22-yard reception from Quinn Ewers vs. Michigan
Gunnar Helm 22-yard reception from Quinn Ewers vs. Michigan
Matthew Golden 20-yard reception from Quinn Ewers vs. Michigan
Jaydon Blue 23-yard reception from Quinn Ewers vs. Michigan
DeAndre Moore 24-yard reception from Quinn Ewers vs. Michigan
Isaiah Bond 33-yard reception from Quinn Ewers vs. Michigan
Ryan Wingo 55-yard rush vs. Michigan
-- 7 vs. Colorado State --
Gunnar Helm 37-yard reception from Quinn Ewers vs. Colorado State
Isaiah Bond 23-yard reception from Quinn Ewers vs. Colorado State
Isaiah Bond 25-yard rush vs. Colorado State
Jerrick Gibson 22-yard rush vs. Colorado State
Ryan Wingo 30-yard reception from Arch Manning vs. Colorado State
Matthew Golden 38-yard reception from Quinn Ewers vs. Colorado State
Johntay Cook 40-yard reception from Arch Manning vs. Colorado State
-- Team Leaders --
Running Backs with 11 total (4 for Blue, 2 for Page, 4 for Wisner, 1 for Gibson)
Gunnar Helm with 10 total (9 from Quinn, 1 from Golden)
Matthew Golden with 8 total (5 from Quinn, 3 from Arch)
Isaiah Bond with 7 total (2 from Quinn, 3 from Arch, 2 rush)
Ryan Wingo with 7 total (4 from Arch, 2 rush, 1 from Quinn)
DeAndre Moore with 7 total (5 from Quinn, 2 from Arch)
Week 10 College Football Top 25 Power Ratings (.977 out of 1.000 = 97.7 Grade)
Tier 1 - (Championship Material)
1. Georgia Bulldogs (6-1) - .980 - IDLE
2. Oregon Ducks (7-0) - .979
3. Texas Longhorns (7-1) - .967
4. Ohio State Buckeyes (6-1) - .957
Tier 2 (Championship Contender)
5. Miami (FL) Hurricanes (8-0) - .941
6. Clemson Tigers (6-1) - .918- IDLE
7. Tennessee Volunteers (6-1) - .917 - IDLE
8. Penn State Nittany Lions (7-0) - .917
Tier 3 (Playoff Material)
9. Alabama Crimson Tide (6-2) - .910
10. Texas A&M Aggies (7-1) - .901
Tier 4 (Playoff Contender)
11. Notre Dame Fighting Irish (7-1) - .811
12. Iowa State (7-0) - .788 - IDLE
13. LSU (6-2) - .785 - (MOVEMENT: -1)
Tier 5 (The Bubble)
14. Kansas State Wildcats (7-1) - .780
15. BYU Cougars (8-0) - .774
16. Ole Miss Rebels (6-2) - .745
17. Boise State (6-1) - .741
18. Indiana Hoosiers (8-0) - .730
Tier 6 (Qualities of a Contender)
19. Colorado Buffaloes (6-2) - .713 - (MOVEMENT: +4)
Tier 7 (Unlikely Contender)
20. Pittsburgh Panthers (7-0) - .708 - (MOVEMENT: +5)
21. SMU Mustangs (6-1) - .704
22. Vanderbilt Commodores (5-2) - .704 - (MOVEMENT: +3)
23. Nebraska Cornhuskers (5-3) - .704
24. Washington State Cougars (7-1) - .704 - (MOVEMENT: +4)
25. Illinois Fighting Illini (6-2) - .703 - (MOVEMENT: -5)
The Next Best (On Watch)
26. Louisville Cardinals (5-3) - .683 - (MOVEMENT: +1)
27. Navy Midshipman (6-1) - .677
28. Army Black Knights (7-0) - .673 - IDLE
29. Memphis Tigers (7-1) - .660
30. Virginia Tech Hokies (5-3) - .658
My Week 10 Heisman Watchlist Update
Tier 1
1. Cameron Ward, Miami (FL) - QB - (68%, 2,746 yards, 24 td 5 int) - 174.7 Rating - (42-186-3 Rushing)
2. Travis Hunter, Colorado - WR/DB - (60-757-8 Receiving) - (21 Tackles, 7 PD, 1 FF and 2 INT on Defense) - (MOVEMENT: +3)
Tier 2
3. Ashton Jeanty, Boise State - RB - (159-1,376-18 Rushing) - (12-50-1 Receiving)
4. Dillon Gabriel, Oregon - QB - (76.2%, 2,371 yards, 18 td 5 int) - 174.8 Rating (36-97-5 Rushing)
Tier 3
5. Cade Klubnik, Clemson - QB - (66.7%, 1,836 yards, 20 td 3 int) - 164.5 Rating - (41-227-4 Rushing)
Tier 4
6. Jaxson Dart, Ole Miss - QB - (70.6%, 2,695 yards, 15 td 3 int) - 180.8 Rating (67-207-3 Rushing)
7. Shedeur Sanders, Colorado - QB - (73.3%, 2,591 yards, 21 td 6 int) - 165.0 Rating (61-(-18)-3 Rushing)
8. Kurtis Rourke, Indiana - QB - (74.6%, 1,941 yards, 15 td 3 int) - 188.7 Rating - (24-45-2 Rushing) - (MOVEMENT: -1)
Dropped from Watchlist
1. Avery Johnson, Kansas State - QB (Week 1)
2. Kyron Drones, Virginia Tech - QB (Week 1)
3. Will Howard, Ohio State - QB (Week 2)
4. Jeremiah Smith, Ohio State - WR - (Week 3)
5. Arch Manning, Texas - QB - (Week 4)
6. Miller Moss, USC - QB - (Week 4)
7. Tetairoa McMillan, Arizona - WR - (Week 5)
8. Drew Allar, Penn State - QB - (Week 5)
9. Nico Iamaleava, Tennessee - QB - (Week 6)
10. Quinn Ewers, Texas - QB - (Week 8)
11. Jalen Milroe, Alabama - QB - (Week 8)
12. Carson Beck, UGA - QB - (Week 8)
13. Garrett Nussmeier, LSU - QB - (Week 9)
Have a great bye week 🤘 To good health and great recovery! Bring on the SWAMP!
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