I doubt it. Stud CB's will mature as noticed when they began to finish out the year, LB corp of Malik, Wheeler, Freeman, Townsend, Hager and possibly Santos with incoming freshman will secure the LB position and the only hit that could occur at DT would be the Green Mile headed for the draft.
The defense actually progressed with youth on the field. Tank wasn't a key and Poona has that wrapped up (we also have Nelson). We need more DT's for depth, but the defense will be better next season.
Jenkins won't be missed. He was already looking over his shoulder at Wheeler.
As for Duke, tons of heart. We have better skilled players on the roster.